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			<title><![CDATA[4. E10030 therapy results in stripping of neovascular pericytes from the CNV]]></title>
			<description><![CDATA[E10030 targets and strongly binds to PDGF, resulting in pericyte stripping.]]></description>
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			<media:title><![CDATA[4. E10030 therapy results in stripping of neovascular pericytes from the CNV]]></media:title>
			<media:description><![CDATA[E10030 targets and strongly binds to PDGF, resulting in pericyte stripping.]]></media:description>
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			<title><![CDATA[3. Lack of significant regression of new blood vessels with Anti-VEGF therapy alone]]></title>
			<description><![CDATA[The neovascular tissue is resistant to regression during a monotherapy anti-VEGF attack due to the presence of the supporting pericytes.]]></description>
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			<media:title><![CDATA[3. Lack of significant regression of new blood vessels with Anti-VEGF therapy alone]]></media:title>
			<media:description><![CDATA[The neovascular tissue is resistant to regression during a monotherapy anti-VEGF attack due to the presence of the supporting pericytes.]]></media:description>
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			<media:copyright><![CDATA[Copyright (c) Ophthotech (http://www.ophthotech.com)]]></media:copyright>
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			<title><![CDATA[2. Increased PDGF expression leads to enhanced pericyte coverage of CNV]]></title>
			<description><![CDATA[Mural cells (pericytes) provide neovascular endothelial cell survival signals by juxtacrine secretion of growth factors such as VEGF.]]></description>
			<link><![CDATA[http://www.ophthotech.com/wp-content/gallery/e10030/e10030b_lg.jpg]]></link>
			<media:content url='http://www.ophthotech.com/wp-content/gallery/e10030/e10030b_lg.jpg' medium='image' />
			<media:title><![CDATA[2. Increased PDGF expression leads to enhanced pericyte coverage of CNV]]></media:title>
			<media:description><![CDATA[Mural cells (pericytes) provide neovascular endothelial cell survival signals by juxtacrine secretion of growth factors such as VEGF.]]></media:description>
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			<media:copyright><![CDATA[Copyright (c) Ophthotech (http://www.ophthotech.com)]]></media:copyright>
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			<title><![CDATA[1. CNV increases PDGF expression]]></title>
			<description><![CDATA[Increased expression of the PDGF molecule is seen in neovascular tissue. PDGF regulates the recruitment and maturation of pericytes (mural cells).]]></description>
			<link><![CDATA[http://www.ophthotech.com/wp-content/gallery/e10030/e10030a_lg.jpg]]></link>
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			<media:title><![CDATA[1. CNV increases PDGF expression]]></media:title>
			<media:description><![CDATA[Increased expression of the PDGF molecule is seen in neovascular tissue. PDGF regulates the recruitment and maturation of pericytes (mural cells).]]></media:description>
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			<media:copyright><![CDATA[Copyright (c) Ophthotech (http://www.ophthotech.com)]]></media:copyright>
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